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How to make a GHK‑Cu serum at home

A copper peptide serum in four steps and ten minutes, with kitchen measures. One gram makes about 27 one-ounce bottles.

Why make it yourself

A finished copper peptide serum sells for $40 to $70 an ounce, yet GHK‑Cu makes up only about 0.1% of the bottle. The rest is water, a humectant and a preservative. With one gram of GHK‑Cu and a base you already like, you can make about 27 one-ounce bottles of serum, at roughly 92¢ of peptide per bottle.

What you need

  • 1 g GHK‑Cu
  • 20 mL (4 tsp) distilled water
  • A base with a pH of 5–7: unscented hyaluronic acid serum, aloe gel or a light lotion, without vitamin C, EDTA, or glycolic or lactic acid
  • Measuring spoons down to ⅛ tsp, a small glass jar and a 1 oz dropper bottle
  • A glass or plastic stirrer, not metal

Step 1: make the stock solution

Stir 1 g of GHK‑Cu into 20 mL (4 tsp) of distilled water until it's clear and deep blue. That's a 5% stock. Date the jar and keep it in the fridge for up to 30 days.

Step 2: add the stock to your base

Fill the dropper bottle with 30 g (1 oz) of base, add ⅛ tsp of stock and turn the bottle gently until the color is even. That's about 0.1% GHK‑Cu, the standard level.

Step 3: choose your strength

Per 100 gStockPer 1 ozUse
¼ tsp1.25 mL8 dropsGentle, first time, eye area
½ tsp2.5 mL⅛ tspStandard, serums and creams
1 tsp5 mL¼ tsp + 5 dropsScalp and hair, masks
2 tsp10 mL½ tsp + ⅛ tspMaximum

Start at standard; use gentle around the eyes. Other batch sizes: dosage calculator.

Step 4: store and use

Use within a month. A few drops on clean skin, morning or evening, before moisturizer.

Troubleshooting

Turned purple or brown? The pH is outside 5 to 7, the serum got warm, or it touched vitamin C, EDTA or metal. Make a fresh batch in a different base.

Making a scalp serum? Use ¼ tsp of stock per 1 oz, or choose AHK‑Cu, the copper peptide formulators use for hair-growth serums. See GHK‑Cu vs AHK‑Cu.